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Identification of a Novel Regulator of Mitochondrial Cell Death Reveals a Promising Target for Cancer Therapy

Wistar researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target.
19-Sep-2019 9:00 AM EDT Add to Favorites

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Major Grant Awarded to Wistar Supports Development of a Novel Therapeutic Approach for Antibiotic-resistant Bacteria

Wistar has received a grant of approximately $4.6 million from the National Institutes of Health in support of innovative research to tackle antibiotic resistance.
12-Sep-2019 3:05 PM EDT Add to Favorites

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Repeated Semen Exposure Promotes Host Resistance to Infection in Preclinical Model of HIV

Contrary to the long-held view that semen can only act as a way to transmit HIV-1 from men to women, scientists at The Wistar Institute and the University of Puerto Rico found that frequent and sustained semen exposure can change the characteristics...
20-Aug-2019 4:05 PM EDT Add to Favorites

Novel Role in Spatial Chromosome Organization Identified for Frequently Mutated Cancer Protein

New research from The Wistar Institute sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers.
22-May-2019 2:05 PM EDT Add to Favorites

Enhanced Anticancer Compound May Allow for Precise Activation and Tracking of Treatment

Wistar and the University of South Florida researchers have advanced a novel compound that specifically targets the endoplasmic reticulum (ER) stress response that is frequently hyperactivated in cancer and promotes survival of cancer cells during...
15-May-2019 12:05 PM EDT Add to Favorites

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Wistar Earns ‘Exceptional’ Rating for NCI Cancer Center Support Grant for the Second Review Cycle in a Row, Demonstrating Strength of Science

The Wistar Institute’s Cancer Center has received an “exceptional” rating on its Cancer Center Support Grant (CCSG) application from the National Cancer Institute (NCI) for the second review cycle in a row and the grant has been recommended...
23-Apr-2019 10:00 AM EDT Add to Favorites

Synthetic DNA-encoded Antibodies Against Zika Virus Shown to be Effective in Preclinical Studies

New approach for delivery of DNA-encoded monoclonal antibodies (DMAbs) has been reported by Wistar scientists. This new technology allows direct production of monoclonal antibody-like molecules in living animals.
5-Apr-2019 11:05 AM EDT Add to Favorites

New Small Molecule Inhibitors Show Potential for Treatment of Epstein-Barr Virus-Associated Cancers

Researchers at The Wistar Institute have created a drug candidate for cancers associated with Epstein-Barr Virus (EBV), the virus that causes infectious mononucleosis.
5-Mar-2019 10:40 AM EST Add to Favorites


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As a nonprofit biomedical research institution, The Wistar Institute is committed to conducting basic research to benefit society and to training the next generation of scientists. Integrity in research is essential to expanding our knowledge of the basic biological processes fundamental to life. All faculty, staff, trainees, and students involved in research at The Wistar Institute are required to maintain the highest standards of ethical conduct in research and to adhere to the rules and regulations of federal agencies governing biomedical research. Faculty and senior research staff are expected to serve as mentors to trainees and students, teaching them the standards of ethical practice in research. Elements of integrity in research include intellectual honesty in conducting and reporting research, maintenance of accurate research records and results, proper allocation of credit among co-authors of studies, fairness in peer review, openness in communications and sharing of resources, transparency in potential conflicts of interest, humane care of animals in the conduct of research, and protection of human subjects in the conduct of research.

Contacts

Darien Sutton
Media Relations & Communications Manager

dsutton@wistar.org

215-898-3988

Tara Yates
Director of Communications
cancer

tyates@wistar.org

215-898-3826

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