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New Mechanism Fueling Brain Metastasis Discovered at Wistar

Wistar scientists described a novel mechanism through which astrocytes, the most abundant supporting cells in the brain, also promote cancer cell growth and metastasis in the brain.
9-Oct-2019 11:05 AM EDT Add to Favorites

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Targeting a Novel Regulator of Mitochondrial Cell Death Delivers Anticancer Activity in Preclinical Studies

A novel anticancer molecule created by researchers at The Wistar Institute showed therapeutic activity in preclinical models of various cancer types.
2-Oct-2019 3:05 PM EDT Add to Favorites

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NIH New Innovator Award Given to Wistar Researcher to Unravel the Metabolic Link Between Diet, Alcohol Consumption and Cancer

The National Institutes of Health (NIH) today announced that Zachary T. Schug, Ph.D., assistant professor in the Molecular & Cellular Oncogenesis Program at Wistar, was awarded the prestigious NIH Director’s New Innovator Award in support of his...
1-Oct-2019 9:40 AM EDT Add to Favorites

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Wistar Receives More than $12 Million to Fund Innovative Clinical Research on the Impact of Opioid Use on Response to Therapy in People Living with HIV

Wistar was awarded two major grants totaling more than $12 million from the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health, to fund an international multidisciplinary clinical research consortium spearheaded by...
24-Sep-2019 10:05 AM EDT Add to Favorites

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Identification of a Novel Regulator of Mitochondrial Cell Death Reveals a Promising Target for Cancer Therapy

Wistar researchers have described the role of mitochondrial fission factor (MFF) in controlling survival of cancer cells, suggesting the protein could represent a promising therapeutic target.
19-Sep-2019 9:00 AM EDT Add to Favorites

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Major Grant Awarded to Wistar Supports Development of a Novel Therapeutic Approach for Antibiotic-resistant Bacteria

Wistar has received a grant of approximately $4.6 million from the National Institutes of Health in support of innovative research to tackle antibiotic resistance.
12-Sep-2019 3:05 PM EDT Add to Favorites

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Repeated Semen Exposure Promotes Host Resistance to Infection in Preclinical Model of HIV

Contrary to the long-held view that semen can only act as a way to transmit HIV-1 from men to women, scientists at The Wistar Institute and the University of Puerto Rico found that frequent and sustained semen exposure can change the characteristics...
20-Aug-2019 4:05 PM EDT Add to Favorites

Novel Role in Spatial Chromosome Organization Identified for Frequently Mutated Cancer Protein

New research from The Wistar Institute sheds light on the function of the ARID1A protein, encoded by a gene that is among the most frequently mutated across human cancers.
22-May-2019 2:05 PM EDT Add to Favorites

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As a nonprofit biomedical research institution, The Wistar Institute is committed to conducting basic research to benefit society and to training the next generation of scientists. Integrity in research is essential to expanding our knowledge of the basic biological processes fundamental to life. All faculty, staff, trainees, and students involved in research at The Wistar Institute are required to maintain the highest standards of ethical conduct in research and to adhere to the rules and regulations of federal agencies governing biomedical research. Faculty and senior research staff are expected to serve as mentors to trainees and students, teaching them the standards of ethical practice in research. Elements of integrity in research include intellectual honesty in conducting and reporting research, maintenance of accurate research records and results, proper allocation of credit among co-authors of studies, fairness in peer review, openness in communications and sharing of resources, transparency in potential conflicts of interest, humane care of animals in the conduct of research, and protection of human subjects in the conduct of research.


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