Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that cells from children with NGLY1 deficiency—a rare disorder first described in 2012—lack sufficient water channel proteins called aquaporins. The discovery was...
13-Jan-2020 5:05 PM EST Add to Favorites
Scientists at Sanford Burnham Prebys have identified a new way to boost the immune system’s ability to fight cancer. The study used a mouse model to identify the importance of the Siah2 protein in the control of immune cells called T regulatory...
3-Jan-2020 11:40 AM EST Add to Favorites
Scientists at Sanford Burnham Prebys Medical Discovery Institute have shown that worms live longer lives if they produce excess levels of a protein, p62, which recognizes toxic cell proteins that are tagged for destruction. The discovery, published...
10-Dec-2019 4:05 PM EST Add to Favorites
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a combination of two anti-cancer compounds that shrank pancreatic tumors in mice—supporting the immediate evaluation of the drugs in a clinical trial. U.S. Food and...
18-Nov-2019 11:00 AM EST Add to Favorites
Sanford Burnham Prebys awarded $3.58 million NIH grant to advance potential treatment for opioid-use disorders
The National Institute on Drug Abuse (NIDA), part of the National Institutes of Health (NIH), awarded a $3.58 million grant to Sanford Burnham Prebys scientist Anthony Pinkerton, Ph.D., to advance a potential treatment for opioid-use disorders,...
21-Oct-2019 1:35 PM EDT Add to Favorites
Scientists at Sanford Burnham Prebys Medical Discovery Institute have developed a machine-learning algorithm that gleans information from microscope images—allowing for high-throughput epigenetic drug screens that could unlock new treatments for...
22-Oct-2019 8:00 AM EDT Add to Favorites
Premature babies have delicate brain tissue that is prone to bleeding and can result in post-hemorrhagic hydrocephalus, a dangerous condition that leads to excess fluid accumulation and brain dysfunction. Now, scientists from Sanford Burnham Prebys...
8-Oct-2019 4:05 PM EDT Add to Favorites
The California Institute for Regenerative Medicine (CIRM) has awarded a $4.96 million grant to Sanford Burnham Prebys Professor Evan Y. Snyder, M.D., Ph.D. The funding will allow Snyder to complete pre-investigational new drug (IND)-enabling...
19-Aug-2019 8:00 AM EDT Add to Favorites
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