Polycyclic Aromatic Hydrocarbon Exposure in Chimney Sweeps; Disruption of Lipid Homeostasis in Neonatal Mouse Brains; and More Featured in September 2019 Toxicological Sciences

Issue Also Contains Papers on Endocrine and Renal Findings in γ-Secretase Inhibitor Avagacestat Studies and Phthalate Exposure During Rat Prostate Development


Newswise — The September 2019 issue of Toxicological Sciences features Tox Spotlight articles on chimney sweeps exposed to polycyclic aromatic hydrocarbons, the relationship between endocrine and renal findings in studies of the γ-secretase inhibitor Avagacestat, environmental exposure to phthalates during prostate development in rats, and the disruption of lipid homeostasis due to environmental chemicals in neonatal mouse brains. There also are Open Access articles on the adaptation of systematic review framework for assessing toxicity tests, using physiologically based kinetic modeling-facilitated reverse dosimetry to predict acetylcholinesterase inhibition, and the decontamination of hair following a hazmat incident.

Highlights of Toxicological Sciences Volume 171, Issue 1:

Toxicological Sciences is the official journal of the Society of Toxicology (SOT), a professional and scholarly organization of more than 7,800 scientists from academic institutions, government, and industry representing the great variety of individuals who practice toxicology around the world.

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