Latest News from: Children's Hospital of Philadelphia

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Scientists Detail how Chromosomes Reorganize after Cell Division

Children's Hospital of Philadelphia

Researchers have discovered key mechanisms and structural details of a fundamental biological process—how a cell nucleus and its chromosomal material reorganizes itself after cell division. The new findings in chromosomal architecture and function may offer important insights into human health and disease.

Channels: All Journal News, Cell Biology, Genetics, Nature (journal),

Released:
4-Dec-2019 4:05 PM EST
Newswise: Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial

Teens with Heart Disease Improve Exercise Capacity in Large Clinical Trial

Children's Hospital of Philadelphia

The largest-ever clinical trial of a medication for pediatric cardiology patients found that an oral drug significantly improved exercise capacity in adolescent patients with severe, congenital single-ventricle heart defects. A study leader says the physiologic benefits represent a milestone in pediatric cardiology.

Channels: Exercise and Fitness, Pharmaceuticals, All Journal News, Cardiovascular Health, Children's Health, Clinical Trials, Heart Disease, Grant Funded News,

Released:
17-Nov-2019 10:45 AM EST
Research Results
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  • Embargo expired:
    14-Nov-2019 11:00 AM EST

Revised Criteria Lead to More Accurate Screening for Eye Disease in Premature Infants

Children's Hospital of Philadelphia

A multicenter group of 41 hospitals led by researchers at Children’s Hospital of Philadelphia (CHOP) has confirmed that an improved method for predicting retinopathy of prematurity (ROP), a leading cause of blindness in children, was able to reduce the number of babies having invasive diagnostic examinations by nearly a third, while raising disease detection up to 100 percent.

Channels: All Journal News, Children's Health, Healthcare, JAMA,

Released:
12-Nov-2019 2:30 PM EST
Research Results
Newswise: Early Spinal Patterns May Predict Scoliosis in Teen Years

Early Spinal Patterns May Predict Scoliosis in Teen Years

Children's Hospital of Philadelphia

A pediatric researcher has identified patterns of spinal curvature in younger children that may be likely to develop into scoliosis by adolescence. Accurately predicting scoliosis, a common, abnormal curvature of the spine, may set the stage for the first-ever methods to prevent the potentially disabling condition.

Channels: All Journal News, Bone Health, Children's Health, Healthcare, Scientific Reports, Nature (journal),

Released:
13-Nov-2019 3:30 PM EST
Research Results
Newswise: Stephan Grupp, MD, PhD, Elected to the National Academy of Medicine

Stephan Grupp, MD, PhD, Elected to the National Academy of Medicine

Children's Hospital of Philadelphia

Stephan Grupp, MD, PhD, Chief of the Cell Therapy and Transplant Section in the Division of Oncology and Director of the Cancer Immunotherapy Program at Children’s Hospital of Philadelphia, has been elected into the National Academy of Medicine (NAM), effective Oct. 1, 2019.

Channels: All Journal News, Cancer, Children's Health, Healthcare,

Released:
21-Oct-2019 3:45 PM EDT
Research Results
Newswise: Children's Hospital of Philadelphia Offers Help and Cure for Picky Eaters

Children's Hospital of Philadelphia Offers Help and Cure for Picky Eaters

Children's Hospital of Philadelphia

Families dealing with the stress and frustration of their child’s overly picky eating habits may have a new addition to their parental toolbox. Pediatric researchers describe a brief group cognitive-behavioral therapy program that provides parents with specific techniques to improve their child’s mealtime behaviors and expand the range of foods their children will eat.

Channels: All Journal News, Behavioral Science, Children's Health, Cognition and Learning, Family and Parenting, Food Science, Health Food, Nutrition,

Released:
21-Oct-2019 2:30 PM EDT
Announcement
Newswise: Beverly Davidson, PhD, Elected to the National Academy of Medicine

Beverly Davidson, PhD, Elected to the National Academy of Medicine

Children's Hospital of Philadelphia

Beverly L. Davidson, PhD, director of the Raymond G. Perelman Center for Cellular and Molecular Therapeutics at Children’s Hospital of Philadelphia, has been elected to the National Academy of Medicine. She is being recognized for her role in developing innovative therapies for fatal, inherited brain disorders.

Channels: Children's Health, Neuro,

Released:
21-Oct-2019 12:05 PM EDT
Research Results
Newswise: Subtle Mitochondrial DNA Mutations Alter Expression of Nuclear Genes, with Profound Clinical Effects

Subtle Mitochondrial DNA Mutations Alter Expression of Nuclear Genes, with Profound Clinical Effects

Children's Hospital of Philadelphia

Subtle changes in the DNA of mitochondria, the tiny power plants in cells, can have profound consequences for a patient’s health. Research on biological mechanisms suggests that relatively minor changes in mitochondrial energy flow and metabolism could offer significant future benefits to patients with complex diseases.

Channels: All Journal News, Cell Biology, Children's Health, Genetics, Grant Funded News,

Released:
15-Oct-2019 4:40 PM EDT
Announcement
Newswise: Genetics Researchers Find New Neurodevelopmental Syndrome
  • Embargo expired:
    3-Oct-2019 11:00 AM EDT

Genetics Researchers Find New Neurodevelopmental Syndrome

Children's Hospital of Philadelphia

Researchers have identified a gene mutation that causes developmental delay, intellectual disability, behavioral abnormalities and musculoskeletal problems in children. Mutations in the NKAP gene cause the condition, called NKAP-related syndrome.

Channels: Children's Health, Genetics, Neuro, All Journal News,

Released:
30-Sep-2019 5:05 PM EDT
Research Results
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  • Embargo expired:
    27-Sep-2019 12:05 AM EDT

First Large-Scale Study of Universal Screening for Autism Raises Critical Questions about Accuracy, Equity

Children's Hospital of Philadelphia

In the first large, real-world study of universal screening for autism spectrum disorder (ASD) in toddlers, researchers at Children’s Hospital of Philadelphia (CHOP) have found that the most widely used and researched screening tool is less accurate than shown in previous studies conducted in research laboratory settings. The new study also revealed significant disparities in detecting early autism symptoms in minority, urban and low-income children.

Channels: All Journal News, Autism, Children's Health,

Released:
24-Sep-2019 10:05 AM EDT
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