Latest News from: Perelman School of Medicine at the University of Pennsylvania

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Embargo will expire:
23-Oct-2019 1:00 PM EDT
Released to reporters:
17-Oct-2019 4:15 PM EDT

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  • Embargo expired:
    17-Oct-2019 1:00 PM EDT

Article ID: 720907

High-Risk Patients Benefit from Undergoing Surgery at Teaching Hospitals

Perelman School of Medicine at the University of Pennsylvania

Patients with a high risk of dying after surgery, including those with multiple chronic diseases, benefit from undergoing general or vascular procedures at a major teaching hospital as opposed to a non-teaching hospital, according to a study from researchers at Penn Medicine and CHOP.

Released:
17-Oct-2019 8:00 AM EDT
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  • Embargo expired:
    17-Oct-2019 1:00 PM EDT

Article ID: 720908

Nationwide Study Aims Improve Long-Term Lung Transplant Outcomes

Perelman School of Medicine at the University of Pennsylvania

As part of an effort to improve long-term outcomes, a national team led by a researcher at Penn Medicine has launched a study--funded by a $9.8 million grant from the NIH--to better understand clinical and biological processes that occur after transplant and lead to the development of these complications.

Released:
17-Oct-2019 8:05 AM EDT
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  • Embargo expired:
    16-Oct-2019 1:00 PM EDT

Article ID: 720658

Failure of Mitochondrial Quality Control Causes Heart Disease

Perelman School of Medicine at the University of Pennsylvania

Researchers at Penn Medicine discovered that a protein called ANT is critical for a quality control process called mitophagy—which helps to ensure the integrity of the mitochondria network by removing damaged mitochondria—and found that ANT mutations that lead to a defective quality control system cause heart disease

Released:
14-Oct-2019 8:05 AM EDT
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  • Embargo expired:
    14-Oct-2019 11:00 AM EDT

Article ID: 720535

Women Have Substantially Less Influence on Twitter than Men in Academic Medicine

Perelman School of Medicine at the University of Pennsylvania

Women who are health policy or health services researchers face a significant disparity in social media influence compared to their male peers, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania. Although the average number of tweets among all researchers tend to be consistent, women trail behind men in follower counts, regardless of how active they are on Twitter. The findings, which hold implications for larger questions around gender disparities in academic medicine, are published today in JAMA Internal Medicine.

Released:
10-Oct-2019 1:05 PM EDT
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  • Embargo expired:
    14-Oct-2019 11:00 AM EDT

Article ID: 720577

Researchers Explore Spinal Discs’ Early Response to Injury and Ways to Improve It

Perelman School of Medicine at the University of Pennsylvania

Researchers showed in animal models that spinal discs' default injury response can be temporarily stopped to allow for better treatment

Released:
11-Oct-2019 9:30 AM EDT
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Article ID: 720676

“Back in Time”: Penn Researchers Unravel the Early Makings of an Exhausted T Cell

Perelman School of Medicine at the University of Pennsylvania

Penn Medicine researchers explore a T cell's path to exhaustion and what triggers it.

Released:
14-Oct-2019 9:30 AM EDT
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Article ID: 720612

New Opioid Prescription Dosages Drop 22 Percent in Penn Medicine’s New Jersey Practices Following Changes to State Law and Health Record Alerts

Perelman School of Medicine at the University of Pennsylvania

The total amount of opioids dispensed per new opioid prescription decreased by 22 percent in Penn Medicine outpatient practices in New Jersey after the state passed a law limiting prescriptions to a five-day supply for new opioid prescriptions. Penn Medicine implemented an electronic health record (EMR) alert, or “nudge,” to notify clinicians if that limit had been reached. The study, published online today in the Journal of General Internal Medicine, is one of the first evaluations of a state law’s impact on prescribing outcomes, and is the first report of an EMR being used to make compliance with prescribing limits easier. Importantly, after the prescribing limit and alert went into effect there was no evidence to suggest pain control worsened.

Released:
11-Oct-2019 1:05 PM EDT
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Article ID: 720504

With $20 Million NIH Grant, Penn Researchers to Develop a Tool to Help Diagnose, Track Parkinson’s Disease

Perelman School of Medicine at the University of Pennsylvania

A special type of PET scan used for imaging the brains of patients with Parkinson’s could be revolutionary for drug development and treatment.

Released:
10-Oct-2019 1:20 PM EDT
Newswise: Algorithm Personalizes Which Cancer Mutations Are Best Targets for Immunotherapy
  • Embargo expired:
    9-Oct-2019 11:00 AM EDT

Article ID: 720274

Algorithm Personalizes Which Cancer Mutations Are Best Targets for Immunotherapy

Perelman School of Medicine at the University of Pennsylvania

As tumor cells multiply, they often spawn tens of thousands of genetic mutations. Figuring out which ones are the most promising to target with immunotherapy is like finding a few needles in a haystack. Now a new model hand-picks those needles so they can be leveraged in more effective, customized cancer vaccines.

Released:
7-Oct-2019 9:00 AM EDT

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