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Mayo Clinic researchers have discovered that subtle structural features in kidneys from living donors that can only be seen with a microscope may predict the risk of transplant failure in recipients. The findings are published online in the Journal of the American Society of Nephrology.
• In analyses of biopsies of deceased donor kidneys, a repeat biopsy often showed very different findings than the initial biopsy, calling into question decisions to decline an organ based on the initial biopsy findings.
• Although the first biopsy findings were not associated with post-transplant outcomes, findings from the second biopsies—which were performed in a relatively standardized manner at one organ procurement organization and read by the same group of pathologists—provided useful information about how well the organ functioned after transplantation.
• Subtle structural features of donated kidneys—which were observed through biopsies taken at the time of donation—were associated with the longevity of organs after they were transplanted.
Research technician Natalie Jones is the lead author on a paper that looked at how scientists model the vulnerability of karst formations around the Grand Canyon. Along with professor Abe Springer, she created a new model that can give land and water managers more information so they can better protect the water system.
The United States currently averages 20 mass shootings per year. Researchers from Michigan State University measured the extent to which mass shootings are committed by domestic violence perpetrators, suggesting how firearm restrictions may prevent these tragedies.
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