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  • Embargo expired:
    1-Aug-2013 2:00 PM EDT

Article ID: 605965

Scripps Research Institute Scientists Find Long-Sought Method to Efficiently Make Complex Anticancer Compound

Scripps Research Institute

Scientists at The Scripps Research Institute have achieved the first efficient chemical synthesis of ingenol, a highly complex, plant-derived compound that has long been of interest to drug developers for its anticancer potential.

Released:
30-Jul-2013 1:00 PM EDT
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  • Embargo expired:
    1-Aug-2013 2:00 PM EDT

Article ID: 606040

The When and Where of the Y: Research on Y Chromosomes Uncovers New Clues About Human Ancestry

Michigan Medicine - University of Michigan

Using advanced analysis of DNA from Y chromosomes from men all over the world, scientists have shed new light on the mystery of when and how a few early human ancestors started to give rise to the incredible diversity of today’s population.

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1-Aug-2013 8:00 AM EDT
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Article ID: 606060

Critical Care Nurse Adds Cochrane Collaboration Research Reviews

American Association of Critical-Care Nurses (AACN)

The American Association of Critical-Care Nurses adds research reviews from The Cochrane Collaboration as a regular department in its clinical practice journal, Critical Care Nurse.

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1-Aug-2013 1:00 PM EDT
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Article ID: 606061

New Treatment Strategy for Breast Cancer Spread to Brain

University of California, Los Angeles (UCLA), Health Sciences

Researchers at UCLA’s Jonsson Comprehensive Cancer Center have successfully combined cellular therapy and gene therapy in a mouse model system to develop a viable treatment strategy for breast cancer that has metastasized to the patient’s brain.

Released:
1-Aug-2013 1:00 PM EDT
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  • Embargo expired:
    1-Aug-2013 12:00 PM EDT

Article ID: 605864

Neuroscientists Find Protein Linked to Cognitive Deficits in Angelman syndrome

New York University

A team of neuroscientists has identified a protein in laboratory mice linked to impairments similar to those afflicted with Angelman syndrome—a condition associated with symptoms that include autism, intellectual disability, and motor abnormalities.

Released:
29-Jul-2013 8:40 AM EDT
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  • Embargo expired:
    1-Aug-2013 12:00 PM EDT

Article ID: 605867

Boning Up: McMaster Researchers Find Home of Best Stem Cells for Bone Marrow Transplants

McMaster University

McMaster University researchers have revealed the location of human blood stem cells that may improve bone marrow transplants. The best stem cells are at the ends of the bone.

Released:
29-Jul-2013 9:00 AM EDT
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  • Embargo expired:
    1-Aug-2013 12:00 PM EDT

Article ID: 605898

UC San Diego Researchers Develop Efficient Model for Generating Human iPSCs

University of California San Diego Health

Researchers at the University of California, San Diego School of Medicine report a simple, easily reproducible RNA-based method of generating human induced pluripotent stem cells (iPSCs) in the August 1 edition of Cell Stem Cell. Their approach has broad applicability for the successful production of iPSCs for use in human stem cell studies and eventual cell therapies.

Released:
29-Jul-2013 1:15 PM EDT
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  • Embargo expired:
    1-Aug-2013 12:00 PM EDT

Article ID: 605911

New Designer Compound Treats Heart Failure by Targeting Cell Nucleus

Case Western Reserve University

Researchers from Case Western Reserve University School of Medicine and the Dana-Farber Cancer Institute have discovered a new molecular pathway responsible for causing heart failure and showed that a first-in-class prototype drug, JQ1, blocks this pathway to protect the heart from damage.

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29-Jul-2013 4:00 PM EDT
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  • Embargo expired:
    1-Aug-2013 12:00 PM EDT

Article ID: 605945

Potential Nutritional Therapy for Childhood Neurodegenerative Disease

University of California San Diego Health

Researchers at the University of California, San Diego School of Medicine have identified the gene mutation responsible for a particularly severe form of pontocerebellar hyplasia, a currently incurable neurodegenerative disease affecting children. Based on results in cultured cells, they are hopeful that a nutritional supplement may one day be able to prevent or reverse the condition.

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30-Jul-2013 12:00 PM EDT
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  • Embargo expired:
    1-Aug-2013 12:00 PM EDT

Article ID: 606022

Sanford-Burnham Researchers Map a New Metabolic Pathway Involved in Cell Growth and Implicated in Cancer as Well as Metabolic Disorders

Sanford Burnham Prebys Medical Discovery Institute

Researchers at Sanford-Burnham Medical Research Institute now have a more complete picture of one particular pathway that can lead to cancer and diabetes. In the study published by Molecular Cell, the scientists uncovered how a protein called p62 has a cascade affect in regulating cell growth in response to the presence of nutrients such as amino acids and glucose.

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31-Jul-2013 4:00 PM EDT
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