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The Greening of Chemistry

Cleaner! Faster! Cheaper! is a rallying cry for chemists working to limit the impact of their work on the environment. Here are a few examples of how chemists funded by NIH are going green by improving the chemical processes used to make medicines, plastics and other products.

Medicine

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Liposome, Micropatterning, Nanoparticle, Drug Delivery, Dip-pen nanolithography, Microarray, Lab On A Chip, Nanotechnology, Chemistry, High Throughput Screening, Cancer, Pharmaceutical

Researcher on Verge of Breakthrough in Drug Creation Process

A Florida State University researcher is developing technologies to miniaturize the first phase of a process used by pharmaceutical companies to discover new drugs. A breakthrough could ultimately lead to personalized and therefore more effective medical treatments, as well as major health care savings.

Medicine

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Case Western Reserve University School Of Medicine, Acute Lymphoblastic Leukemia, theranostic, Pediatric Oncology, ACS Chemical Biology

Researchers Develop First “Theranostic” Treatment for ALL

A team of researchers at Case Western Reserve University School of Medicine has developed the first “theranostic” agent for the treatment of acute lymphoblastic leukemia (ALL). ALL is the most common type of childhood cancer diagnosed in approximately 5,000 new cases each year in the United States.

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Researchers Discover New Method of Making Nanoparticles

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An engineering researcher at the University of Arkansas and his colleagues at the University of Utah have discovered a new method of making nanoparticles and nanofilms to be used in developing better electronic devices, biosensors and certain types of high-powered and highly specific microscopes used for scientific research.

Medicine

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Alzheimer's Disease, Enzyme, Biological Chemistry

Laboratory Research Shows Promising Approach to Preventing Alzheimer's

As scientists struggle to find an effective way to prevent Alzheimer's disease, researchers at the University of Wisconsin School of Medicine and Public health may have found a new approach to interrupting the process that leads to the devastating disease.

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Meeting Biofuel Production Targets Could Change Agricultural Landscape

Almost 80 percent of current farmland in the U.S. would have to be devoted to raising corn for ethanol production in order to meet current biofuel production targets with existing technology, a new study has found. An alternative, according to a study in ACS’ journal Environmental Science & Technology, would be to convert 60 percent of existing rangeland to biofuels.

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New Hybrid “NOSH Aspirin” as Possible Anti-Cancer Drug

Scientists have combined two new “designer” forms of aspirin into a hybrid substance that appears more effective than either of its forebears in controlling the growth of several forms of cancer in laboratory tests. Their report on the new NOSH-aspirin, so named because it releases nitric oxide (NO) and hydrogen sulfide (H2S), appears in the journal ACS Medicinal Chemistry Letters.

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Adapting Personal Glucose Monitors to Detect DNA

An inexpensive device used by millions of people with diabetes could be adapted into a home DNA detector that enables individuals to perform home tests for viruses and bacteria in human body fluids, in food and in other substances, scientists are reporting in a new study. The report on this adaptation of the ubiquitous personal glucose monitor, typically used to test blood sugar levels, appears in ACS’ journal Analytical Chemistry.

Science

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Fermi dyad, Molecular Dynamics, Isotopes

Toppling Raman Shift in Supercritical Carbon Dioxide

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Just as a wine glass vibrates and sometimes breaks when a diva sings the right note, carbon dioxide vibrates when light or heat serenades it. When it does, carbon dioxide exhibits a vibrational puzzle known as Fermi resonance. Now, researchers studying geologic carbon storage have learned a bit more about the nature of carbon dioxide.

Science

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Biofuels, cellulosic biofuels, advanced biofuels, Biochemistry, Plant Sciences

Chemists Aid Study of Mutated Plants That May Be Better for Biofuels

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A new study says genetic mutations in plants could make it easier to break down plant cellulose to the sugars that are fermented into biofuels. The researchers' findings are published in the Proceedings of the National Academy of Sciences.







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