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Newswise: Calcium Signaling Identified as Exploitable Target in Addressing Drug Resistance to Non-Hodgkin Lymphoma Treatment

Calcium Signaling Identified as Exploitable Target in Addressing Drug Resistance to Non-Hodgkin Lymphoma Treatment

Rutgers Cancer Institute of New Jersey

Gene expression profiling and other analyses conducted by Rutgers Cancer Institute of New Jersey researchers and colleagues examining drug resistance to a common antibody therapy for non-Hodgkin lymphoma have identified calcium signaling as a novel and exploitable target in overcoming this treatment obstacle. Results are being presented at the American Society of Hematology Annual Meeting.

Channels: Medical Meetings, All Journal News, Cancer, Drug Resistance,

Released:
2-Dec-2019 2:35 PM EST
Newswise: Drug-Resistant Staph Can Spread Easily in Household Environments
  • Embargo expired:
    26-Nov-2019 6:30 PM EST

Drug-Resistant Staph Can Spread Easily in Household Environments

Washington University in St. Louis

Once rare, the superbug methicillin-resistant Staphylococcus aureus (MRSA) infects hundreds of thousands of people in the U.S. each year and kills about 20,000. New research led by Washington University School of Medicine in St. Louis sheds light on how MRSA is introduced into households and, once there, how it can spread among family members, including the furry ones. Understanding MRSA’s transmission dynamics is critical to devising effective preventive tactics.

Channels: Drug Resistance, Infectious Diseases, Patient Safety, Public Health, All Journal News,

Released:
18-Nov-2019 3:45 PM EST
Research Results
Newswise: Study Shows Evolution Turns Genes Back On to Regain Function

Study Shows Evolution Turns Genes Back On to Regain Function

Stony Brook University

Genes often mutate and lose their function over long-term evolution, which could be good if that stops drug resistance or cancer. A study by Stony Brook University researchers, published online in PNAS, shows that evolution can exploit positive feedback (PF) within cells to restore gene function.

Channels: All Journal News, Drug Resistance, Engineering, Genetics, National Institutes of Health (NIH), PNAS,

Released:
25-Nov-2019 2:30 PM EST
Research Results
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  • Embargo expired:
    25-Nov-2019 11:00 AM EST

New flu drug drives drug resistance in influenza viruses

University of Wisconsin-Madison

University of Wisconsin-Madison researchers examined the effects of baloxavir treatment on influenza virus samples collected from patients before and after treatment.

Channels: All Journal News, Children's Health, Drug Resistance, Pharmaceuticals, Influenza, Japan News, Nature (journal),

Released:
19-Nov-2019 1:45 PM EST
Research Results
Newswise: Potent antimicrobial found that shows promise in fighting staph infections
  • Embargo expired:
    25-Nov-2019 11:00 AM EST

Potent antimicrobial found that shows promise in fighting staph infections

McMaster University

After screening thousands of small molecules, the research team discovered a potent new antimicrobial they are calling MAC-545496 that is active against MRSA. Unlike conventional antibiotics, this new antimicrobial neither kills the staph infection nor halts its growth on its own, so the potential for antimicrobial resistance may be considerably lessened.

Channels: All Journal News, Drug Resistance, Infectious Diseases, Nature (journal),

Released:
22-Nov-2019 1:05 PM EST
Research Results

Stop asking for that antibiotic

Beaumont Health

“We believe Beaumont has a duty to raise awareness and help change attitudes about antibiotics and behaviors that cause antibiotic resistance,” said Dr. Sam Flanders, senior vice president and chief quality and safety officer of Beaumont Health. “Antibiotics save lives. But when they’re used too much, they can lead to antibiotic resistance.”

Channels: All Journal News, Children's Health, Drug Resistance, Infectious Diseases, Public Health,

Released:
22-Nov-2019 10:10 AM EST
Research Results
Newswise: Strength in numbers: Crowdsourcing challenge seeks new methods to combat drug-resistant malaria

Strength in numbers: Crowdsourcing challenge seeks new methods to combat drug-resistant malaria

University of Notre Dame

A team of researchers at Notre Dame put out a call to the masses, enlisting researchers, data scientists and health professionals to analyze genomic data from emerging drug-resistant malaria parasites and gain a better understanding of the mechanisms of resistance.

Channels: All Journal News, Drug Resistance, Infectious Diseases, Pharmaceuticals, Public Health, Nature (journal),

Released:
19-Nov-2019 4:10 PM EST
Policy

Superbug battle: Bacteria structure may be key to new antibiotics

Cornell University

Cornell researchers have uncovered the structure of a regulatory mechanism unique to bacteria, opening the door for designing new antibiotics targeted to pathogens.

Channels: All Journal News, Cell Biology, Drug Resistance, Pharmaceuticals, Nature (journal),

Released:
18-Nov-2019 3:55 PM EST
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