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Newswise: Researchers create accurate model of organ scarring using stem cells in a lab

Researchers create accurate model of organ scarring using stem cells in a lab

University of California, Los Angeles (UCLA), Health Sciences

A team led by Dr. Brigitte Gomperts at UCLA has developed a “scar in a dish” model that uses multiple types of cells derived from human stem cells to closely mimic the progressive scarring that occurs in human organs. The researchers used this model to identify a drug candidate that stopped the progression of and even reversed fibrosis in animal models.

Channels: All Journal News, Cancer, Cell Biology, Stem Cells, Cell (journal),

Released:
10-Dec-2019 5:05 PM EST
  • Embargo expired:
    5-Dec-2019 11:00 AM EST

More Than a Watchdog

Harvard Medical School

Study in mice shows the nervous system not only detects the presence of Salmonella in the gut but actively stops the organism from infecting the body Nerves in the gut prevent Salmonella infection by shutting the cellular gates that allow bacteria to invade the intestine and spread beyond it As a second line of defense, gut neurons help avert Salmonella invasion by maintaining the levels of key protective microbes in the gut Findings reveal prominent role for nervous system in infection protection and regulation of immunity

Channels: All Journal News, Digestive Disorders, Immunology, Infectious Diseases, Microbiome, National Institute of Allergy and Infectious Diseases (NIAID), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH), Cell (journal),

Released:
2-Dec-2019 2:45 PM EST
Research Results
Newswise: : The Greenest Diet: Bacteria Switch to Eating Carbon Dioxide

: The Greenest Diet: Bacteria Switch to Eating Carbon Dioxide

Weizmann Institute of Science

Weizmann Institute scientists have converted bacteria to consume CO2 – basically, to live on air – instead of sugar. Such bacteria may contribute to new, carbon-efficient technologies, from food production to green fuels.

Channels: All Journal News, Engineering, Green Tech, Microbiome, Cell (journal),

Released:
27-Nov-2019 2:15 PM EST
Research Results
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  • Embargo expired:
    26-Nov-2019 11:00 AM EST

Hibernating Mammals Arouse Hope for Genetic Solutions to Obesity, Metabolic Diseases

University of Utah Health

University of Utah Health scientists say they have detected new genetic clues about hibernation that could lead to better understanding and treatment of obesity and metabolic disorders that afflict millions of people worldwide.

Channels: All Journal News, Cancer, Digestive Disorders, Obesity, Cell (journal),

Released:
22-Nov-2019 6:00 AM EST
Research Results
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  • Embargo expired:
    26-Nov-2019 11:00 AM EST
Released:
26-Nov-2019 9:00 AM EST
Research Results
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Turning Key Metabolic Process Back On Could Make Sarcoma More Susceptible to Treatment

Perelman School of Medicine at the University of Pennsylvania

Soft tissue sarcoma cells stop a key metabolic process which allows them to multiply and spread, and so restarting that process could leave these cancers vulnerable to a variety of treatments

Channels: All Journal News, Blood, Cancer, National Cancer Institute (NCI), Cell (journal), Grant Funded News,

Released:
26-Nov-2019 3:00 AM EST
Research Results
Newswise: Non-Coding DNA Located Outside Chromosomes May Help Drive Glioblastoma
  • Embargo expired:
    21-Nov-2019 11:00 AM EST

Non-Coding DNA Located Outside Chromosomes May Help Drive Glioblastoma

University of California San Diego Health

According to a new Cell study, extra DNA scooped up and copied alongside cancer-causing genes helps keep tumors going — elements that could represent new drug targets for brain tumors and other cancers notoriously difficult to treat.

Channels: All Journal News, Cancer, Cell Biology, Genetics, Neuro, Cell (journal),

Released:
18-Nov-2019 4:15 PM EST
Research Results
Newswise: New screening method identifies inhibitors of cancer cell metabolism

New screening method identifies inhibitors of cancer cell metabolism

University of California, Los Angeles (UCLA), Health Sciences

A new screening system developed by scientists at the UCLA Jonsson Comprehensive Cancer Center leverages redundancy in an important component of a cell – nucleotide metabolism – to help identify new drugs that specifically and potently block processes that are essential for cancer cell growth.

Channels: All Journal News, Cancer, Cell Biology, Healthcare, Pharmaceuticals, Cell (journal),

Released:
18-Nov-2019 4:30 PM EST
Research Results
Newswise: Master regulator in mitochondria is critical for muscle function and repair

Master regulator in mitochondria is critical for muscle function and repair

Thomas Jefferson University

New study identifies how loss of mitochondrial protein MICU1 disrupts calcium balance and causes muscle atrophy and weakness

Channels: Cell Biology, Neuro, Cell (journal), All Journal News,

Released:
14-Nov-2019 4:35 PM EST
Research Results
  • Embargo expired:
    14-Nov-2019 11:00 AM EST

Genes Borrowed From Bacteria Allowed Plants to Move to Land

University of Alberta

Natural genetic engineering allowed plants to move from water to land, according to a new study by an international group of scientists from Canada, China, France, Germany, and Russia.

Channels: Cell Biology, Chemistry, Evolution and Darwin, Genetics, Plants, Staff Picks, Cell (journal), All Journal News,

Released:
7-Nov-2019 2:55 PM EST
Research Results

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