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Newswise: Helper Protein Worsens Diabetic Eye Disease

Helper Protein Worsens Diabetic Eye Disease

Johns Hopkins Medicine

In a recent study using mice, lab-grown human retinal cells and patient samples, Johns Hopkins Medicine scientists say they found evidence of a new pathway that may contribute to degeneration of the light sensitive tissue at the back of the eye. The findings, they conclude, bring scientists a step closer to developing new drugs for a central vision-destroying complication of diabetes that affects an estimated 750,000 Americans.

Channels: All Journal News, Diabetes, Pharmaceuticals, Vision, National Eye Institute (NEI), Grant Funded News,

Released:
27-Nov-2019 8:00 AM EST
Newswise: Finding A Cell’s True Identity

Finding A Cell’s True Identity

Johns Hopkins Medicine

Scientists have long sorted cells into different varieties based on their appearance under a microscope or, for differences that are more visually subtle, based on the behavior of a handful of genes. But in a bid to reveal even more distinctive differences and similarities, researchers from the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins Institute for Genetic Medicine and the Johns Hopkins Department of Neuroscience developed two new artificial intelligence methods that decipher complex gene activity controlling cell fate decisions in retina development and relate this gene activity to what occurs in other tissues and across different species.

Channels: All Journal News, Grant Funded News, Cancer, Cell Biology, Artificial Intelligence, Cell (journal),

Released:
28-May-2019 10:00 AM EDT
Research Results
Newswise: Research Suggests Revision to Common View on How Retinal Cells in Mammals Process Light

Research Suggests Revision to Common View on How Retinal Cells in Mammals Process Light

Johns Hopkins Medicine

Johns Hopkins Medicine scientists say that new experiments with mouse eye tissues strongly suggest that a longstanding “textbook concept” about the way a mammal’s retina processes light needs a rewrite.

Channels: All Journal News, Grant Funded News,

Released:
16-May-2019 9:00 AM EDT
Research Results
Newswise: Experimental Drug Delivers One-Two Punch to Vision Loss

Experimental Drug Delivers One-Two Punch to Vision Loss

Johns Hopkins Medicine

In studies with lab-grown human cells and in mice, Johns Hopkins Medicine researchers have found that an experimental drug may be twice as good at fighting vision loss as previously thought.

Channels: Grant Funded News, Vision, All Journal News,

Released:
10-Apr-2019 10:00 AM EDT
Research Results
Newswise: Enzyme Helps Build Motor That Drives Neuron Death
  • Embargo expired:
    6-Aug-2018 11:00 AM EDT

Enzyme Helps Build Motor That Drives Neuron Death

Vanderbilt University

The process, discovered in the axons of neurons, is implicated in Alzheimer’s, amyotrophic lateral sclerosis, traumatic brain injury and other diseases or injuries to the nervous system.

Channels: All Journal News, Grant Funded News, Alzheimer's and Dementia, Cell Biology, Neuro,

Released:
2-Aug-2018 12:00 PM EDT
Research Results

A sprinkle of platinum nanoparticles onto graphene makes brain probes more sensitive

University of California San Diego

Graphene electrodes could enable higher quality brain imaging thanks to new research by a team of engineers and neuroscientists at UC San Diego. The researchers developed a technique, using platinum nanoparticles, to lower the impedance of graphene electrodes by 100 times while keeping them transparent. In tests on transgenic mice, the electrodes were able to record and image neuronal activity (calcium ion spikes) at of large groups of neurons and individual brain cells.

Channels: All Journal News, Engineering, Nanotechnology, Neuro, Technology, Grant Funded News, Local - California,

Released:
14-Jun-2018 2:05 PM EDT
Research Results
Newswise: Low Vision Research Shifts Into Overdrive

Low Vision Research Shifts Into Overdrive

NIH, National Eye Institute (NEI)

Tim Goetz drives about 200,000 miles each year. Remarkably, Goetz is legally blind. Research funded by the National Eye Institute (NEI) is helping Goetz and others like him get or stay behind the wheel while keeping roads safe for everyone.

Channels: Grant Funded News, Vision, Local - Maryland, Local - DC Metro, National Institutes of Health (NIH), National Eye Institute (NEI),

Released:
22-Feb-2018 8:00 AM EST
Research Results
Newswise: NEI-Funded Research Suggests Repetitive Strain From Eye Movement May Play a Role in Glaucoma

NEI-Funded Research Suggests Repetitive Strain From Eye Movement May Play a Role in Glaucoma

NIH, National Eye Institute (NEI)

Common, unavoidable eye movements may be a cause of glaucoma in people with normal intraocular pressure (normal-tension glaucoma), according to new research supported by the National Eye Institute. The findings suggest that over time eye movement strains the optic nerve, the bundle of nerve fibers between the eye and brain. The research may also explain why tension-lowering eye drops can improve normal-tension glaucoma. Glaucoma is the second leading cause of blindness worldwide and January is Glaucoma Awareness Month.

Channels: All Journal News, Vision, Grant Funded News, Local - Maryland, Local - DC Metro, National Institutes of Health (NIH), National Eye Institute (NEI),

Released:
4-Jan-2018 10:05 AM EST
Feature
Newswise: Scientists Find Key to Regenerating Blood Vessels
  • Embargo expired:
    23-Nov-2017 5:00 AM EST

Scientists Find Key to Regenerating Blood Vessels

Sanford Burnham Prebys Medical Discovery Institute

Florida researchers have identified a signaling pathway that is essential for angiogenesis, the growth of new blood vessels from pre-existing vessels. The findings, published in Nature Communications, may improve current strategies to improve blood flow in ischemic tissue, such as that found in atherosclerosis and peripheral vascular disease associated with diabetes.

Channels: Cell Biology, Chemistry, Diabetes, Regenerative Medicine, Nature (journal), Local - California, All Journal News, Grant Funded News,

Released:
20-Nov-2017 2:00 PM EST
Research Results


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