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Immunology

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Medicine

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Brain Cancer, Glioblastoma, Poliovirus therapy, Immuno-therapy

Poliovirus Therapy Induces Immune Responses Against Cancer

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An investigational therapy using modified poliovirus to attack cancer tumors appears to unleash the body’s own capacity to fight malignancies by activating an inflammation process that counter’s the ability of cancer cells to evade the immune system.

Medicine

Science

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gene activation, Genetics, Cell And Developmental Biology, DNA, Leukemia, Lymphoma

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 21-Sep-2017 12:00 PM EDT

Medicine

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Sarcoma, Cancer, Immunotherapy, durvalumab/MEDI4736, Tremelimumab, Radiation, Soft Tissue Cancer

New Clinical Trial Explores Combining Immunotherapy and Radiation for Newly Diagnosed Sarcoma Patients

University of Maryland School of Medicine researchers are investigating a new approach to treat high-risk soft-tissue sarcomas by combining two immunotherapy drugs with radiation therapy to stimulate the immune system to destroy the main tumor as well as leftover microscopic cancer cells that may seed other tumors.

Medicine

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Immune Cells, Macrophages, Wound Repair, Intestine, Inflammatory Bowel Disease, treatments, Tim Denning, Institute for Biomedical Sciences

Immune Cells Produce Wound Healing Factor, Could Lead To New IBD Treatment

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Specific immune cells have the ability to produce a healing factor that can promote wound repair in the intestine, a finding that could lead to new, potential therapeutic treatments for inflammatory bowel disease (IBD), according to a new research study.

Medicine

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Pancreatic Cancer, Chemotherapy, Chemotherapy resistance, Bacteria, cytidine deaminase , Straussman

How Bacteria Hinder Chemotherapy

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Dr. Ravid Straussman and colleagues have discovered that bacteria not only live in pancreatic cancer, but are able to render a chemo drug ineffective. Fortunately, it appears that taking antibiotics allows the chemo to work again.

Medicine

Science

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Immunotheapy, Cancer, Oxygen, T Cells, Shakhar

Altitude Training for Cancer-Fighting Cells

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Training at altitude – meaning under low-oxygen conditions – turns athletes into super-performers. Likewise, Prof. Guy Shakhar has found, oxygen-starved T cells become super-effective at attacking cancer. These T cells could provide an immediate way to improve cancer immunotherapy.

Medicine

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Robert Froemke, Dan Littman, Pew, Nyu Langone

Two NYU School of Medicine Researchers Awarded New Pew Research Prizes

A research team at NYU School of Medicine and its Skirball Institute of Biomolecular Medicine is one of six from across the United States to receive newly established innovation funds from the Pew Charitable Trusts’ biomedical programs.

Medicine

Science

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Hanna Gray, Diversity, Howard Hughes Medical Institute, Early Career, Fellowship, Science Fellowships, Hanna H. Gray Fellows Program

HHMI Selects 15 Hanna Gray Fellows to Support Diversity in Science

HHMI announces the selection of 15 exceptional early career scientists as the first group of HHMI Hanna Gray Fellows. The 2018 Hanna Gray Fellows competition is now open, with applications due on January 10, 2018.

Medicine

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Acute Promyelocytic Leukemia, Immune Cells, immune suppression, Prostate Cancer

Ludwig Scientists Discover Complex Axis of Immune Suppression Exploited by Cancers

A Ludwig Cancer Research study has uncovered a new mechanism by which cancer cells evade destruction by the immune system. The paper, led by Camilla Jandus of the Lausanne Branch of the Ludwig Institute for Cancer Research, describes how immune cells known as group 2 innate lymphoid cells (ILC2s) are recruited by leukemic cells to suppress an essential anticancer immune response.

Science

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Ricin, Bio Weapons, Toxicity, Cell Biology, Therapy

Ricin Only Lethal in Combination with Sugar

Researchers at the Austrian Academy of Sciences’ Institute for Molecular Biotechnology (IMBA) have discovered a means of immunising cells against the biological weapon ricin, as reported in the current issue of Cell Research.







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