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Preemies Activism, Craniofacial Conditions, New Therapy Lessons, and More in the Children's Health News Source

Click here for the latest research and features on Children's Health.

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The One Gene, Menu Labeling, Holiday Food Stress, and More in the Obesity News Source

Click here to go directly to Newswise's Obesity News Source

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Diabetes & Endocrinology, Diabetes, bioartificial pancreas, Pancreas Transplant

Can a Common Ingredient in Laundry Detergent Help Advance Diabetes Research?

Being able to build a bioartificial pancreas offers the potential to cure type 1 diabetes. A major challenge with the effort is how to supply the structure with enough oxygen to keep the cells alive. Now, new research suggests that oxygen-generating compounds found in some laundry detergents may play a key role.

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Microbiome, Crohn's Diesease, Gastroenterology, bacterial enzyme

A Clean Slate: Engineering the Gut Microbiome with “Good” Bacteria May Help Treat Crohn’s Disease

Penn Medicine researchers have singled out a bacterial enzyme behind an imbalance in the gut microbiome linked to Crohn’s disease. The new study, published online this week in Science Translational Medicine, suggests that wiping out a significant portion of the bacteria in the gut microbiome, and then re-introducing a certain type of “good” bacteria that lacks this enzyme, known as urease, may be an effective approach to better treat these diseases.

Medicine

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cancer, , gastric and esophageal adenocarcinoma, extensive genetic variation , genetic instability , metastatic sites

Wider Sampling of Tumor Tissues May Guide Drug Choice, Improve Outcomes

By focusing on genetic variations within a primary tumor, differences between the primary and a metastatic tumor, and additional diversity from tumor DNA in the blood stream, physicians can make better treatment choices for patients with gastric and esophageal adenocarcinoma. This study challenges current guidelines and supports evaluation of metastatic lesions and circulating tumor DNA.”

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Colon Cancer, Colectomy, Colon Surgery, Chemotherapy, NCCN, NCCN Guidelines in Oncology, MD Anderson Cancer Center, health services research

Quality of Care for Older Texas Patients with Colon Cancer on the Rise, Still Room for Improvement

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Research from The University of Texas MD Anderson Cancer Center finds adherence to surgical treatment guidelines has improved significantly among older Texas patients with colon cancer since 2001, while adherence to chemotherapy guidelines has remained largely unchanged. The study, published today in Cancer, identifies factors influencing adherence rates, including socioeconomic status and access to skilled physicians.

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Stem Cell Based Tissues, stem cell bio-manufacturing, Gastro Intestinal, induced pluripotent stem, technology acceleration, pediatrics disorders, Organ Transplant, liver transplant, Hirschsprung disease, Intestinal Disorders, stem cell medicine, Research & Development, Cincinnati Children's Hospital Medical Center, press release, Medical Center

Cincinnati Children’s Launches Center for Stem Cell and Organoid Medicine

Seven years ago Cincinnati Children’s scientists first used pluripotent stem cells to mimic natural human development and grow working human intestine in a lab. Today medical center doctors can bioengineer the gastrointestinal tissues of sick children to find clues about a child’s disease and how to treat it. Cincinnati Children’s is building on this early research advancement in personalized medicine by launching the Center for Stem Cell and Organoid Medicine (CuSTOM).

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Abdominal Aortic Aneurysm, tryptophan metabolism, Ming-Hui Zou, Center for Molecular and Translational Medicine , Georgia Research Alliance Eminent Scholar, Georgia Research Alliance, National Institutes of Health, Angiotensin Ii

Abdominal Aortic Aneurysm Linked to Dysregulated Tryptophan Metabolism, Study Finds

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Researchers have found a link between dysregulated tryptophan metabolism and abdominal aortic aneurysm, a life-threatening vascular disease, according to a new study led by Georgia State University.

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Are Delays in Colon Cancer Treatment Safe?

This Canadian study provides further evidence that even surgical treatment delays of several weeks do not adversely influence survival. Patients who require further consultations or investigations preoperatively may safely have their surgery moderately delayed in order to minimize their perioperative risk without any evidence that this will compromise treatment outcomes.

Science

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toxicological sciences, Toxicology, TCE, PCE, Aflatoxin, AHR, Society Of Toxicology

Research Articles on Transcriptomics to Aid Risk Assessment, Pregnancy and Carcinogen Metabolism, and More Featured in Toxicological Sciences

Editor's Highlights include papers on aryl hydrocarbon receptor activation and neutrophil function; transcriptomic analysis of TCE and PCE in the liver and kidney; functional genomics of TCE metabolites genotoxicity; and increased aflatoxin b1 damage in pregnant mice.







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