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Oral Hormone-Blocking Drug May Help with Heavy Menstrual Bleeding

Thomas Jefferson University

In women with uterine fibroids, the drug elagolix suppresses ovarian hormone production and prevents heavy menstrual bleeding

Channels: All Journal News, Clinical Trials, Healthcare, OBGYN, Pharmaceuticals, Surgery, Women's Health, NEJM,

Released:
23-Jan-2020 12:50 PM EST
Newswise: Researchers uncover two-drug combo that halts the growth of cancer cells

Researchers uncover two-drug combo that halts the growth of cancer cells

UT Southwestern Medical Center

UT Southwestern Simmons Cancer Center researchers have discovered a two-drug combo that halts the growth of cancer cells that carry HER2 mutations.

Channels: Cancer, Clinical Trials, Drug Resistance, Healthcare, Pharmaceuticals, National Cancer Institute (NCI), All Journal News,

Released:
23-Jan-2020 12:10 PM EST
Research Results
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Adrenaline Handbrake

Harvard Medical School

Researchers have solved the long-standing mystery of how adrenaline regulates a key class of membrane proteins that are responsible for initiating the contraction of heart cells. The findings provide a mechanistic description of how adrenaline stimulates the heart and present new targets for cardiovascular drug discovery, including the potential development of alternative therapeutics to beta-blockers.

Channels: All Journal News, Cardiovascular Health, Cell Biology, Pharmaceuticals, National Center for Advancing Translational Sciences (NCATS), National Institutes of Health (NIH), Nature (journal),

Released:
23-Jan-2020 12:05 PM EST
Research Results
Newswise: Researchers Uncover Mechanism for How Common Gene Therapy Vectors Enter Cells

Researchers Uncover Mechanism for How Common Gene Therapy Vectors Enter Cells

Massachusetts Eye and Ear

Researchers have identified a novel cellular entry factor for adeno-associated virus vector (AAV) types—the most commonly used viral vectors for in vivo gene therapy.

Channels: All Journal News, Cell Biology, Clinical Trials, Genetics, Pharmaceuticals, Vision, National Institutes of Health (NIH),

Released:
23-Jan-2020 11:15 AM EST
Research Results
Embargo will expire:
30-Jan-2020 11:00 AM EST
Released to reporters:
23-Jan-2020 11:05 AM EST

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Research Results
Newswise: Study Finds a Drug-Like Compound That May Prevent Parkinson’s Disease Progression

Study Finds a Drug-Like Compound That May Prevent Parkinson’s Disease Progression

Rutgers Robert Wood Johnson Medical School

A collaboration between scientists at Rutgers University and The Scripps Research Institute led to the discovery of a small molecule that may slow down or stop the progression of Parkinson’s disease.

Channels: All Journal News, Chemistry, Neuro, Parkinson’s Disease, Pharmaceuticals, Technology, National Institutes of Health (NIH),

Released:
23-Jan-2020 10:55 AM EST
Research Results
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A Menu of Brain Cancer Treatments

University of New Mexico Comprehensive Cancer Center

Sara Piccirillo, PhD, is passionate about finding a way to beat glioblastoma, the most aggressive type of brain cancer. Her research focuses on a feature of glioblastoma tumors that appears to be the source of their strength: the extreme differences among their tumor cells.

Channels: Cancer, Healthcare, Neuro, Pharmaceuticals,

Released:
23-Jan-2020 8:05 AM EST
Research Results
  • Embargo expired:
    23-Jan-2020 5:00 AM EST

New Drug Target for Prostate Cancer Found in the Non-Coding Genome

University Health Network (UHN)

Scientists at Princess Margaret Cancer Centre have identified the drivers of a crucial gene involved in prostate cancer, revealing new targets for drug design.

Channels: Cancer, Healthcare, Men's Health, Pharmaceuticals, Cell Biology, Genetics, Nature (journal), All Journal News,

Released:
22-Jan-2020 5:55 PM EST
Announcement
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Surprise discovery shakes up our understanding of gene expression

University of Chicago

A group of University of Chicago scientists has uncovered a previously unknown way that our genes are made into reality. Rather than directions going one-way from DNA to RNA to proteins, the latest study shows that RNA itself modulates how DNA is transcribed—using a chemical process that is increasingly apparent to be vital to biology. The discovery has significant implications for our understanding of human disease and drug design.

Channels: Cell Biology, Chemistry, Genetics, Pharmaceuticals, All Journal News,

Released:
22-Jan-2020 2:50 PM EST
Research Results
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  • Embargo expired:
    22-Jan-2020 1:00 PM EST

Researchers Reverse HIV Latency, Important Scientific Step Toward Cure

University of North Carolina School of Medicine

Overcoming HIV latency – activating HIV in CD4+ T cells that lay dormant – is a needed step toward a cure. Scientists at UNC-Chapel Hill, Emory University, and Qura Therapeutics – a partnership between UNC and ViiV Healthcare – showed it’s possible to drive HIV out of latency in two animal models.

Channels: AIDS and HIV, Blood, Healthcare, Immunology, Infectious Diseases, Pharmaceuticals, National Institute of Allergy and Infectious Diseases (NIAID), Nature (journal), All Journal News,

Released:
21-Jan-2020 11:10 AM EST
Research Results


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