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Glycosylation, Stem Cell, Ricin

Glycosylation: Mapping Uncharted Territory

Glycosylation is the most abundant protein modification - over half of the proteins in our cells are ‘decorated’ with glycans. These sugar structures alter protein activities in all organisms – from bacteria to human - influencing fundamental processes, like protein folding and transport, cell migration, cell-cell interactions, and immune responses.

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Stem Cells Development Regeneration, Bone morphogenetic protein, sensory interneurons, Neurons, spinal cord development, Spinal Cord Injury, Sci Treatment And Recovery, Paralysis, Sensory Neurons, Neuron development, Neuroscience, Embryonic Stem Cell Research, Central Nervous System Injuries, spinal cord injury research

Research Redefines Proteins’ Role in the Development of Spinal Sensory Cells

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A recent study led by Samantha Butler at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA has overturned a common belief about how a certain class of proteins in the spinal cord regulate the formation of nervous system cells—called neurons—during embryonic development.

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Clues on a Successful Vaccine, Tick Saliva, Natural Immune Response, and More in the AIDS and HIV News Source

The latest research, features, and experts on HIV and AIDS.

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Temple, Temple University Hospital, Temple Hospital , Philadelphia, North Philadelphia, Grant, Research Grant, Developed

$11.6 Million NIH Grant Supports Temple Researchers’ Exploration of New Cell-Free Stem Cell-Based Possibilities in Heart Repair

The incidence of heart disease is on the rise, and new therapeutic strategies are needed.

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Checking Your Neck, Colon Cancer Screening, New Microfluidic Device, and More in the Cancer News Source

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Cancer, Clinical Trial, clinical trial enrollment, clinical trial for cancer, Immunotherapy Clinical Trials, Immunotherapy, Stem Cells, stem cell clinical trials , Sarcoma, Blood Stem Cells, Cancer Treatment, Cirm

UCLA opens first engineered blood stem cell clinical trial for cancers with the NY-ESO-1 tumor marker

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Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have initiated a phase 1 clinical trial to test a novel cancer treatment for certain kinds of cancers that have a specific tumor marker called NY-ESO-1.

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San Diego, Palm Beach Florida, Antibodies, Stem Cells, induced pluripotent stem (iPS) cells, The Scripps Research Institute

Outside-In Reprogramming: Antibody Study Suggests A Better Way to Make Stem Cells

Scientists at The Scripps Research Institute (TSRI) have found a new approach to the “reprogramming” of ordinary adult cells into stem cells.

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Motor Neurons, Neurodegenative Disease, Developmental Biology

Human Skin Cells Transformed Directly Into Motor Neurons

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In new research, scientists at Washington University School of Medicine in St. Louis have converted skin cells from healthy adults directly into motor neurons without going through a stem cell state. The technique makes it possible to study motor neurons of the human central nervous system in the lab. Unlike commonly studied mouse motor neurons, human motor neurons growing in the lab would be a new tool since researchers can’t take samples of these neurons from living people but can easily take skin samples.

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Penn Medicine, Telomeres, Perelman School of Medicine at the University of Pennsylvania, Muscular Dystrophy Research

Researchers Find Shortened Telomeres Linked to Dysfunction in Duchenne Muscular Dystrophy

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Researchers from the Perelman School of Medicine at the University of Pennsylvania have made a discovery about muscular dystrophy disorders that suggest new possibilities for treatment. In a study published today online in Stem Cell Reports, researchers found that stem cells in the muscles of muscular dystrophy patients may, at an early age, lose their ability to regenerate new muscle, due to shortened telomeres

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Stem Cells, Bone Marrow, Stem Cell Transplantation

Researchers Point Way to Improved Stem Cell Transplantation Therapies

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Researchers in Germany have demonstrated that hematopoietic stem cell (HSC) transplants can be improved by treatments that temporarily prevent the stem cells from dying. The approach, which is described in a paper to be published September 7 in The Journal of Experimental Medicine, could allow those in need of such transplants, including leukemia and lymphoma patients, to be treated with fewer donor stem cells while limiting potential adverse side effects.







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