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Stem Cells

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Medicine

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Ut Southwestern, TBI

Deletion of a Stem Cell Factor Promotes TBI Recovery in Mice

esearchers found that conditional deletion of Sox2 – the gene encoding the SOX2 stem cell transcription factor – and the associated dampening of astrocyte reactivity appear to promote functional recovery, including behavioral recovery, after traumatic brain injury, said Dr. Zhang, a W.W. Caruth, Jr. Scholar in Biomedical Research.

Medicine

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Stem Cells, Feinberg School of Medicine, Northwestern Medicine, JAMA, Peripheral Arterial Disease

Stem Cells Fail to Alleviate Peripheral Artery Disease

A stem cell therapy did not improve walking ability in people with peripheral artery disease, although exercise did lead to significant improvements, according to a new study. This is the largest trial of this type of therapy in people with blockages in leg arteries. Scientists were disappointed that stem cell therapy didn’t improve walking, because earlier research suggested it could be beneficial.

Medicine

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Stem Cell, iPSC, Differentiation, Neuronal Cell, Microrna, P53, Cell Fate Determination

Finding a Key to Unlock Blocked Differentiation in Microrna-Deficient Embryonic Stem Cells

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In a study published in Stem Cell Reports, Rui Zhao and colleagues have partly solved a long-unanswered basic question about stem cells — why are pluripotent stem cells that have mutations to block the production of microRNAs unable to differentiate?

Medicine

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Stem Cell, ophtahlmology

Stem Cell Therapy Shows Promise for Common Cause of Blindness

Results from two early clinical trials show that it may be possible to use human embryonic stem cells as treatment for the dry form of macular degeneration, according to presentations given today at AAO 2017, the 121st Annual Meeting of the American Academy of Ophthalmology.

Science

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Neurobiology, Stem Cell

UW Scientists Create a Recipe to Make Human Blood-Brain-Barrier

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In a report published this week (Nov. 8, 2017) in Science Advances, researchers from the University of Wisconsin-Madison detail a defined, step-by-step process to make a more exact mimic of the human blood-brain-barrier in the laboratory dish. The new model will permit more robust exploration of the cells, their properties and how scientists might circumvent the barrier for therapeutic purposes.

Medicine

Science

Life

Business

Law and Public Policy

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Rural Health, Healthcare, Robert Wood Johnson Foundation, National 4-H Council, Appalachia, Health Disparities, Racial Disparities, Prevention, Health Policy

Closing the Rural Health Gap: Media Update from RWJF and Partners on Rural Health Disparities

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Rural counties continue to rank lowest among counties across the U.S., in terms of health outcomes. A group of national organizations including the Robert Wood Johnson Foundation and the National 4-H Council are leading the way to close the rural health gap.

Medicine

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Windows into the Brain, Ancient Reflex, Double Vision Report, and More in the Vision News Source

The latest research and feature news on vision in the Vision News Source

Science

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Neurogenesis, Alzheimber's Disease, Neuroscience, Epilelpsy, Depression, schizophenia

How Do Adult Brain Circuits Regulate New Neuron Production?

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UNC School of Medicine neuroscientists discover a long-distance brain circuit that controls the production of new neurons in the hippocampus. Research could have implications for understanding and treating many brain disorders, including epilepsy, schizophrenia, depression, and Alzheimer’s disease

Medicine

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Stem Cell Therapies, Nitric Oxide, anti-aging, cell failure, Oral Health, antiseptic mouthwash, Regenerative Medicine, Regenerative Medicine Advanced Therapy, Disease Prevention, CVD prevention, Leafy Greens

Nitric Oxide Production in Patients is Critical for Stem Cell Function

Nathan Bryan, PH.D., one of the nation’s leading experts on critically important role of nitric oxide in health and disease prevention, told attendees of the Pacific Regenerative Medicine 2017 Conference this morning that, “Stem cells are the future of medicine and are required for our body to heal itself; however, their success depends on the body producing enough nitric oxide to support their healing properties. Simply, put, without the right amount of NO in the body, our own stem cells fail to function and furthermore, those receiving stem cell therapy may have limited success without proper NO production.”

Medicine

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Duke University School of Medicine, Duke University Medical Center, Duke Health, Joanne Kurtzberg, Stem Cells Therapy, Umbilical Cord Blood, Umbilical cord blood cells, Cerebral Palsy, cerebral palsy rehabilitation, brain injury and repair, Cord Blood Cells, Cord blood transplantation, cord blood infusion, Cord Blood Banking

Umbilical Cord Blood Improves Motor Skills in Some Children With Cerebral Palsy

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An infusion of cells from a child’s own umbilical cord blood appears to improve brain connectivity and motor function in children with spastic cerebral palsy, according to a randomized clinical trial published this week by Stem Cells Translational Medicine.







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