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University of Colorado Cancer Center study shows healthy form of the leukemia-causing gene MLL may push pluripotent stem cells (which have proven difficult to use in human patients) to become durable hematopoietic stem cells (which are usable in patients, but have until now been impossible to make).

Channels: All Journal News, Blood, Cancer, Cell Biology, Stem Cells, Cancer Center Featured Story 2, Grant Funded News,

Keywords: Leukemia, Childhood Leukemia, MLL gene, Blood Stem Cells, Stem Cells, hematopoetic stem , pluripotent stem (iPS) cells , University Of Colorado Cancer Center, patricia ernst

Two different UC San Diego research teams identified the same molecule — αvβ5 integrin — as Zika virus’ key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink brain cancer stem cells.

Channels: Cancer, Cell Biology, Children's Health, Healthcare, Infectious Diseases, OBGYN, Stem Cells, Vaccines, Zika Virus, National Institutes of Health (NIH), Cell (journal), Embargoed Feed - hidden, All Journal News,

Keywords: zika, Brian Cancer, Glioblastoma, Neurobiology, Virology, Microbliology, Cell Biology, Infectious Diseases, Molecular Biology, Brain Tumor, zika virus, Integrin, Cancer, microcephaly

A nanoparticle carrier system that could eliminate the need for bone marrow transplants, which are both expensive and difficult for patients to undergo. The University of Delaware's Emily Day, an assistant professor of biomedical engineering, is developing a platform that could treat stem cells directly without the need to remove them from the body.

Channels: AIDS and HIV, Biotech, Blood, Healthcare, Stem Cells,

Keywords: Biotechnology, Cancer, HIV, Biomedical Engineering, Blood Stem Cell

A new study from Washington University School of Medicine in St. Louis suggests that extremely rare, harmful genetic mutations present in healthy donors’ stem cells — though not causing health problems in the donors — may be passed on to cancer patients receiving stem cell transplants, potentially creating health problems for the recipients. Among the concerns are heart damage, graft-versus-host disease and possible new leukemias.

Channels: Blood, Cancer, Stem Cells, Transplantation, Embargoed Feed - hidden, All Journal News,

Keywords: Stem Cell Transplant, Bone Marrow Transplant, Graft Versus Host Disease, Blood Cancers

In the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) outline distinct and critical changes to stem cells in males during adolescence.

Channels: Cancer, Cell Biology, Children's Health, Stem Cells, Cell (journal), All Journal News,

Keywords: Puberty, Developmental Biology, Cancer

Five new physicians have joined the medical staff at John Theurer Cancer Center at Hackensack University Cancer Center in New Jersey:

Channels: Cancer, Healthcare, In the Workplace, Stem Cells, social media distr - auto for marked clients,

Scientists at Los Alamos and international partners have created the first 3-D images of a special type of RNA molecule that is critical for stem cell programming and known as the “dark matter” of the genome.

Channels: Aging, Artificial Intelligence, Cardiovascular Health, Genetics, Stem Cells, Technology, Nature (journal), All Journal News,

Below are summaries of recent Fred Hutch research findings with links for additional background and media contacts.

Channels: Addiction, All Journal News, Blood, Cancer, Cell Biology, Government/Law, Healthcare, Immunology, Public Health, Smoking, Stem Cells, U.S. Politics, Healthcare Channel Featured Story TOP, Nature (journal), Cancer Center Featured Story 2, Medical Meetings,

Keywords: Immunotheapy, CRISPR, CAR T cell therapy

After decades of effort, scientists use induced pluripotent stem cells to model human spine development Findings provide proof of existence of a segmentation clock in humans guiding spine formation Work sets stage for better understanding of musculoskeletal and metabolic disorders, including congenital scoliosis, muscular dystrophy and type 2 diabetes

Channels: Bone Health, Neuro, Stem Cells, National Institutes of Health (NIH), Nature (journal), Embargoed Feed - hidden, All Journal News,

Keywords: human spine, spine formation, cellular clock

Study shows Colorado drug SVC112 stops production of proteins that cancer stem cells need to survive and grow

Channels: Cancer, Pharmaceuticals, Stem Cells, Cancer Center Featured Story 2, All Journal News,

Keywords: svc112, Cancer, Head And Neck Cancer, University Of Colorado Cancer Center, cancer drug development