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Newswise: Modifier Gene May Explain Why Some with Cystic Fibrosis are Less Prone to Infection

Modifier Gene May Explain Why Some with Cystic Fibrosis are Less Prone to Infection

University of California San Diego Health

People with cystic fibrosis who carry genetic variants that lower RNF5 gene expression have more mutant CFTR protein on cell surfaces. Even if the CFTR protein isn’t fully functional, it’s better than none, and may explain why some with cystic fibrosis are less prone to infection than others.

Channels: All Journal News, Cell Biology, Genetics, Infectious Diseases, Respiratory Diseases and Disorders,

Released:
10-Dec-2019 11:20 AM EST
Newswise: Why Doesn’t Deep-Brain Stimulation Work for Everyone?
  • Embargo expired:
    10-Dec-2019 11:00 AM EST

Why Doesn’t Deep-Brain Stimulation Work for Everyone?

Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have mapped nine functional networks in the deep-brain structures of 10 healthy people, an accomplishment that could lead to improvements in deep-brain stimulation therapy for severe cases of Parkinson’s disease and other neurological conditions.

Channels: Cell Biology, Neuro, Parkinson’s Disease, Staff Picks, All Journal News, Grant Funded News,

Released:
6-Dec-2019 4:05 PM EST
Research Results
Newswise: ASH: Research revises classification of acute myeloid leukemia and myelodysplastic syndrome

ASH: Research revises classification of acute myeloid leukemia and myelodysplastic syndrome

St. Jude Children's Research Hospital

Results from a study conducted by St. Jude Children’s Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.

Channels: Blood, Cancer, Cell Biology, Medical Meetings,

Released:
10-Dec-2019 8:15 AM EST
Research Results
Newswise: Artificial Cells Act More Like the Real Thing

Artificial Cells Act More Like the Real Thing

Penn State College of Engineering

Researchers develop protocells that better mimic living cells to help understand cell movement

Channels: Cell Biology, Chemistry, Engineering, All Journal News,

Released:
9-Dec-2019 1:55 PM EST
Research Results
Newswise: Scientists show thin metal mesh loaded with T cells shrinks solid tumors
  • Embargo expired:
    9-Dec-2019 11:00 AM EST

Scientists show thin metal mesh loaded with T cells shrinks solid tumors

Fred Hutchinson Cancer Research Center

Within weeks, CAR T cells targeting ovarian cancer cleared tumors in 70% of treated mice, shows study in Nature Biomedical Engineering. (Note: Images available for media use).

Channels: All Journal News, Cancer, Cell Biology, Women's Health, Nature (journal),

Released:
6-Dec-2019 11:00 AM EST
Research Results
Newswise: Dana-Farber scientists present promising findings in multiple myeloma at ASH Annual Meeting
  • Embargo expired:
    9-Dec-2019 7:45 AM EST

Dana-Farber scientists present promising findings in multiple myeloma at ASH Annual Meeting

Dana-Farber Cancer Institute

Results of studies on a novel agent to treat multiple myeloma and a combination therapy aimed at slowing the progression of a precursor myeloma condition are among reports being presented by Dana-Farber Cancer Institute investigators at the ASH Annual Meeting.

Channels: Blood, Cancer, Cell Biology, Medical Meetings,

Released:
6-Dec-2019 8:30 AM EST
Research Results

Pioneering research gives fresh insight into 1 of the pivotal building blocks of life

University of Exeter

Pioneering research gives fresh insight into one of the pivotal building blocks of life

Channels: All Journal News, Cell Biology, Genetics,

Released:
9-Dec-2019 3:05 AM EST
Research Results
Newswise: 218967_web.jpg

Dendrites filtering neuron's excitement

Kyoto University

In mere milliseconds trillions of chemical reactions ignite signals that travel across the billions of neurons in our brain. As we go through our daily lives and absorb new knowledge these neurons begin to modify themselves and change their signaling properties.

Channels: All Journal News, Biotech, Cell Biology, Neuro,

Released:
9-Dec-2019 2:05 AM EST
Research Results
Newswise: Genomic features of AML in patients over age 60 can predict success of bone marrow stem cell transplant, research shows
  • Embargo expired:
    7-Dec-2019 8:45 AM EST

Genomic features of AML in patients over age 60 can predict success of bone marrow stem cell transplant, research shows

Dana-Farber Cancer Institute

For older patients with acute myeloid leukemia (AML), the prospects for success of a stem cell transplant can often be predicted based on the particular set of genetic mutations within the tumor cells, investigators at Dana-Farber Cancer Institute and other research centers will report today at the ASH Annual Meeting.

Channels: Blood, Cancer, Cell Biology, Medical Meetings,

Released:
6-Dec-2019 8:30 AM EST
Research Results
Newswise: Technique shows how individual cancer cells react to drugs

Technique shows how individual cancer cells react to drugs

University of Washington School of Medicine

A new technique reported in Science offers more detail, at the single cell level, on how large, pooled samples of various cells react to drugs or other agents. The data might reveal mode of action or the effect of genetic differences in varying responses.

Channels: All Journal News, Cancer, Cell Biology, Genetics, Pharmaceuticals, Grant Funded News,

Released:
6-Dec-2019 1:05 PM EST
Research Results

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