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Article ID: 695145

Researchers Find Genetic Aberrations Responsible for Congenital Diseases That Are Undetectable by Conventional Genetic Screening

Mount Sinai Health System

The research team identified novel epigenetic mutations to be a significant contributor to neurodevelopmental disorders and congenital anomalies

Released:
25-May-2018 10:05 AM EDT
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Embargo will expire:
28-May-2018 11:00 AM EDT
Released to reporters:
24-May-2018 4:35 PM EDT

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 28-May-2018 11:00 AM EDT

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Article ID: 695033

The Gene Editing Institute of Christiana Care Receives First-Ever Life Sciences and Bio Innovation Award from Philadelphia-Israeli Chamber of Commerce

Christiana Care Health System

For ground-breaking scientific research in gene editing and an innovative partnership with Jerusalem-based NovellusDx to advance personalized cancer treatment, the Gene Editing Institute of the Helen F. Graham Cancer Center & Research Institute at Christiana Care received the inaugural Life Sciences and Bio Innovation Award from the Philadelphia-Israeli Chamber of Commerce on May 22.

Released:
23-May-2018 3:05 PM EDT
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Article ID: 695018

Researchers investigate link between DNA replication in HPV and cancer

University of Delaware

University of Delaware researchers are investigating genetic variations in DNA replication of human papillomaviruses (HPV) and its correlation with HPV-related cancers. The research illustrates specific changes in DNA sequences in HPV that correlate with cancer prognosis.

Released:
23-May-2018 12:05 PM EDT
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  • Embargo expired:
    23-May-2018 10:00 AM EDT

Article ID: 694816

HHMI Bets Big On 19 New Investigators

Howard Hughes Medical Institute (HHMI)

HHMI invests $200 million in a small cadre of leading scientists, challenging them to push the limits of what we know about biology.

Released:
18-May-2018 12:05 PM EDT
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Article ID: 694913

Embryonic Gene Regulation Through Mechanical Forces

University of Vienna

sDuring embryonic development genetic cascades control gene activity and cell differentiation. In a new publication of the journal PNAS, the team of Ulrich Technau of the Department of Molecular Evolution and Development at the University of Vienna reported that besides the genetic program, also mechanical cues can contribute to the regulation of gene expression during development.

Released:
22-May-2018 5:05 AM EDT
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Article ID: 694802

New Mechanism Essential for Eye Lens Development Identified

University of Delaware

A team led by a University of Delaware researcher has identified the protein essential for eye lens development and clear vision. Without the protein, eyes will form cataracts; with it, lens cells are cleared and ready to see. The work is providing fundamental new knowledge on the basic underlying mechanisms involved in eye development.

Released:
18-May-2018 10:05 AM EDT
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  • Embargo expired:
    18-May-2018 9:00 AM EDT

Article ID: 694530

Cardiomyopathy Mutation Reduces Heart’s Ability to Vary Pumping Force, Study Reveals

The Rockefeller University Press

Researchers from Washington State University have discovered how a genetic mutation linked to hypertrophic cardiomyopathy disrupts the heart’s normal function. The study, which will be published May 18 in the Journal of General Physiology, reveals that the mutation prevents the heart from increasing the amount of force it produces when it needs to pump additional blood around the body.

Released:
14-May-2018 1:05 PM EDT
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  • Embargo expired:
    17-May-2018 2:00 PM EDT

Article ID: 694664

Scientists Analyze First Ancient Human DNA From Southeast Asia

Harvard Medical School

Harvard Medical School researchers lead the first whole-genome analysis of ancient human DNA from Southeast Asia Study identifies at least three major waves of human migration into the region over the last 50,000 years, each shaping the genetics of Southeast Asia “to a remarkable extent” Findings reveal a complex interplay among archaeology, genetics and language

Released:
16-May-2018 10:35 AM EDT
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Article ID: 694701

Improving Survival in Pancreatic Cancer with Platinum-Based Chemotherapy

Johns Hopkins Medicine

A small study of adults with the most common form of pancreatic cancer adds to evidence that patients with BRCA1 or BRCA2 gene mutations long linked to a high risk of breast cancer have poorer overall survival rates than those without the mutations.

Released:
17-May-2018 8:00 AM EDT
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