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Medicine

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Cancer’s Gene-Determined “Immune Landscape” Dictates Progression of Prostate Tumors

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The field of immunotherapy – the harnessing of patients’ own immune systems to fend off cancer – is revolutionizing cancer treatment today. However, clinical trials often show marked improvements in only small subsets of patients, suggesting that as-yet unidentified variations among tumors result in distinct paths of disease progression and response to therapy.

Science

Channels:

Fungi, Aspergillus, Genomics, Energy, Environment, Bioenergy, Biofuels, Biotechnology, Industrial Applications, genes, secondary metabolites, DOE Office of Science

All in the Family: Focused Genomic Comparisons

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In the Proceedings of the National Academy of Sciences, a team led by researchers at the Technical University of Denmark, the DOE Joint Genome Institute and the Joint BioEnergy Institute report the first outcome from the large-scale sequencing of 300+ Aspergillus species.

Medicine

Channels:

Malaria, Infectious Disease, Genetics, Pharmacology, Whole Genome Analysis, Chemogenetics

Researchers Map Druggable Genomic Targets in Evolving Malaria Parasite

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Researchers at University of California San Diego School of Medicine, with colleagues across the country and around the world, have used whole genome analyses and chemogenetics to identify new drug targets and resistance genes in 262 parasite cell lines of Plasmodium falciparum — protozoan pathogens that cause malaria — that are resistant to 37 diverse antimalarial compounds.

Medicine

Science

Channels:

Neural Stem Cell, Neurogenesis, Neurogenetics, Schizophrenia, Adhd Attention Deficit Disorder, Depression, Gene Expression

Genetic ‘Switches’, Mapped for First Time, Drive Human Brain Development

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UCLA researchers have developed the first map of gene regulation in human neurogenesis, the process by which neural stem cells turn into brain cells and the cerebral cortex expands in size. The scientists identified factors that govern the growth of our brains and, in some cases, set the stage for several brain disorders that appear later in life

Science

Channels:

Epilepsy, Epilepsia, Health, Medicine, Mental Health, Depression, bipolar, Seizures, Rutgers University-New Brunswick, Rutgers, Genetics, genes, New Jersey, NJ, Mood Disorders, Brain, Neurological, Neurons, Nerve Cells, dysthymic disorder, Major Depressive Disorder, Hippocrates, melancholy

Epileptic Seizures and Depression May Share a Common Genetic Cause, Study Suggests

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From the time of Hippocrates, physicians have suspected a link between epilepsy and depression. Now, for the first time, scientists at Rutgers University–New Brunswick and Columbia University have found evidence that seizures and mood disorders such as depression may share the same genetic cause in some people with epilepsy, which may lead to better screening and treatment to improve patients’ quality of life.

Medicine

Channels:

the Mount Sinai Health System, Icahn School of Medicine at Mount Sinai, Genetic Investigation of Anthropometric Traits, Nature Genetics, Obesity, Personalized Medicine, Metabolism, BMI, DNA

Large-Scale Study to Pinpoint Genes Linked to Obesity

Findings provide genetic basis underlying body weight and obesity risk.

Medicine

Life

Social and Behavioral Sciences

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Mental Illness, Depression, Alcoholism, American Sociological Association, genetic problem, Stress

Oversimplifying Beliefs About Causes of Mental Illness May Hinder Social Acceptance

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Belief that mental illness is biological has increased among both health experts and the public in recent years. But campaigns to treat it as a disease and remove stigma may be lacking because other factors, such as bad character and upbringing, still are viewed as playing a role, a Baylor University study has found.

Medicine

Channels:

oncotype dx, Breast Cancer, high risk score, low risk score, Chemotherapy

Gene Test to Predict Breast Cancer Recurrence Less Cost Effective in Real World Practice

The most commonly used gene expression profile test, Oncotype DX®, used to help predict breast cancer recurrence may not be as cost-effective as once thought, say a team of researchers.

Science

Channels:

Rhino, Rhinoceros, Halmos College of Natural Sciences and Oceanography, Cindy Harper, D.V.M., University of Pretoria, St. Petersburg University, Theodosius Dobzhansky Center for Genome Bioinformatics, Genetics, DNA, Conservation, Genome

NSU Researcher Part of Team Using DNA to Protect the Rhinoceros From Extinction

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New Genetics Database helping Protect Rhinoceros from Poaching; Results Leading to Increased Prosecution

Medicine

Channels:

Thyroid, thyroid and pregnancy, Pregnancy, Thyroid Cancer, Thyroid Awareness, Self Exam, Thyroid Disease, Thyroid Diseases, Hypothyroid, Hypothyroidism, Hypothyroidism during pregnancy, Hyperthyroid, Hyperthyroidism, Hormone, Hormones and Cancer, Thyroid Nodule, Thyroid Nodules, Thyroid Awareness Month, Mount Sinai Health System, Icahn School of Medicine, Hea

January Is Thyroid Awareness Month

Mount Sinai Doctors Stress Importance of Early Detection and Announce Expansion of Thyroid Services in NYC







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